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Probiotics And Stomach Health
- Sep 27, 2018 -

In 1982, Australian academics Barry Marshall and robin warren won the Nobel Prize in physiology or medicine for their discovery of helicobacter pylori. H.pylori has been confirmed to be closely associated with chronic gastritis, peptic ulcer, gastric mucosa associated lymphoid tissue lymphoma, and gastric cancer. Especially in the chronic gastritis, peptic ulcer has a significant role in the pathogenesis, almost 100% chronic gastritis, more than 90% duodenal ulcer and more than 70% gastric ulcer detected positive helicobacter pylori (HP) test.

Although the combined treatment of helicobacter pylori infection with multiple antibiotics is of positive clinical significance, the eradication rate of helicobacter pylori is reduced due to the emergence of bacterial resistance, and long-term unreasonable application of antibiotics can cause gastrointestinal dysfunction and gastrointestinal flora imbalance. Probiotics have an inhibitory effect on helicobacter pylori, which causes chronic gastritis and gastric cancer, and can inhibit the colonization and activity of helicobacter pylori. Certain probiotics produce bacteriocins that inhibit the growth of helicobacter pylori. A large number of living probiotics can also interfere with or block the adhesion of helicobacter pylori to the gastric mucosa surface through appropriate methods. Probiotics can not only resist helicobacter pylori infection, but also regulate the immune function of the body, improve the gastrointestinal microecological environment and improve the compliance of helicobacter pylori eradication.

Clinical and experimental model studies have shown that lactobacillus acidophilus secretions can inhibit the growth of helicobacter pylori (in vitro), while lactobacillus gesellarii, lactobacillus yoritchii and LG21 can inhibit the growth of helicobacter pylori in vivo and reduce gastritis. Placebo-controlled studies have shown that probiotics can reduce the side effects of standard triple therapy. Daily ingestion of inactivated lactobacillus acidophilus fermentation liquid has been shown to increase the efficiency of eradicating helicobacter pylori infection. A triple therapy study of 9 children with gastritis showed that fermented milk of dietary lactobacillus dn-114001 had enhanced the effect of helicobacter pylori eradication.

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